Role of attentional resources on gait performance in Huntington's disease
Identifieur interne : 000281 ( France/Analysis ); précédent : 000280; suivant : 000282Role of attentional resources on gait performance in Huntington's disease
Auteurs : Arnaud Delval [France] ; Pierre Krystkowiak [France] ; Marie Delliaux [France] ; Kathy Dujardin [France] ; Jean-Louis Blatt [France] ; Alain Destée [France] ; Philippe Derambure [France] ; Luc Defebvre [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-04-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Adult, Attention, Biomechanical Phenomena, Executive function, Gait Disorders, Neurologic (etiology), Gait Disorders, Neurologic (physiopathology), Humans, Huntington Disease (complications), Huntington Disease (physiopathology), Huntington disease, Huntington's disease, Middle Aged, Motor Activity, Nervous system diseases, Neuropsychological Tests, Performance, Time Factors, attention, dual‐task, executive functions, gait.
- MESH :
- complications : Huntington Disease.
- etiology : Gait Disorders, Neurologic.
- physiopathology : Gait Disorders, Neurologic, Huntington Disease.
- Adult, Attention, Biomechanical Phenomena, Humans, Middle Aged, Motor Activity, Neuropsychological Tests, Time Factors.
Abstract
Patients with Huntington's disease (HD) suffer from cognitive deficits with impaired executive functions, including limited attentional resources. We sought to use a dual‐task paradigm to evaluate attentional demands and the ability of patients with HD to concentrate on two tasks simultaneously. We analyzed the interference effects of cognitive and motor tasks on walking in HD and the contribution of clinical symptoms to gait disturbances. Patients and controls were asked to perform either a motor task (carrying a tray with four glasses), a cognitive task (counting backwards), or no task at all while walking at their preferred speed. Kinematic spatial parameters, temporal parameters, and angular parameters related to gait were recorded in 15 patients and 15 controls by means of a videomotion analysis system. Gait instability was assessed using the stride‐to‐stride variability of the various gait parameters. For patients with HD, performing a concurrent cognitive task resulted in a lower gait speed (compared with free walking), with decreased cadence and stride length. However, this effect was not observed in controls. Performing a motor task did not change any kinematic gait parameters in either HD or control subjects. We found correlations between gait speed in the dual cognitive/walking task on one hand and the motor UHDRS score, cognitive status and executive function on the other. Patients with HD had greater difficulty walking while performing a concurrent cognitive task; the drain on attentional resources deteriorated walking performance. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21896
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-04-15">2008-04-15</date><biblScope unit="vol">23</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="684">684</biblScope><biblScope unit="page" to="689">689</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">593E7CDF927BA47365C8269C7B4EBF7023CA2CAA</idno><idno type="DOI">10.1002/mds.21896</idno><idno type="ArticleID">MDS21896</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Attention</term><term>Biomechanical Phenomena</term><term>Executive function</term><term>Gait Disorders, Neurologic (etiology)</term><term>Gait Disorders, Neurologic (physiopathology)</term><term>Humans</term><term>Huntington Disease (complications)</term><term>Huntington Disease (physiopathology)</term><term>Huntington disease</term><term>Huntington's disease</term><term>Middle Aged</term><term>Motor Activity</term><term>Nervous system diseases</term><term>Neuropsychological Tests</term><term>Performance</term><term>Time Factors</term><term>attention</term><term>dual‐task</term><term>executive functions</term><term>gait</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Gait Disorders, Neurologic</term><term>Huntington Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Attention</term><term>Biomechanical Phenomena</term><term>Humans</term><term>Middle Aged</term><term>Motor Activity</term><term>Neuropsychological Tests</term><term>Time Factors</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Attention</term><term>Chorée de Huntington</term><term>Fonction exécutive</term><term>Pathologie du système nerveux</term><term>Performance</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with Huntington's disease (HD) suffer from cognitive deficits with impaired executive functions, including limited attentional resources. We sought to use a dual‐task paradigm to evaluate attentional demands and the ability of patients with HD to concentrate on two tasks simultaneously. We analyzed the interference effects of cognitive and motor tasks on walking in HD and the contribution of clinical symptoms to gait disturbances. Patients and controls were asked to perform either a motor task (carrying a tray with four glasses), a cognitive task (counting backwards), or no task at all while walking at their preferred speed. Kinematic spatial parameters, temporal parameters, and angular parameters related to gait were recorded in 15 patients and 15 controls by means of a videomotion analysis system. Gait instability was assessed using the stride‐to‐stride variability of the various gait parameters. For patients with HD, performing a concurrent cognitive task resulted in a lower gait speed (compared with free walking), with decreased cadence and stride length. However, this effect was not observed in controls. Performing a motor task did not change any kinematic gait parameters in either HD or control subjects. We found correlations between gait speed in the dual cognitive/walking task on one hand and the motor UHDRS score, cognitive status and executive function on the other. Patients with HD had greater difficulty walking while performing a concurrent cognitive task; the drain on attentional resources deteriorated walking performance. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Nord-Pas-de-Calais</li></region><settlement><li>Lille</li></settlement><orgName><li>Université Lille 2</li><li>Université Lille Nord de France</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name></noRegion><name sortKey="Blatt, Jean Ouis" sort="Blatt, Jean Ouis" uniqKey="Blatt J" first="Jean-Louis" last="Blatt">Jean-Louis Blatt</name><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><name sortKey="Delliaux, Marie" sort="Delliaux, Marie" uniqKey="Delliaux M" first="Marie" last="Delliaux">Marie Delliaux</name><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name><name sortKey="Derambure, Philippe" sort="Derambure, Philippe" uniqKey="Derambure P" first="Philippe" last="Derambure">Philippe Derambure</name><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name><name sortKey="Dujardin, Kathy" sort="Dujardin, Kathy" uniqKey="Dujardin K" first="Kathy" last="Dujardin">Kathy Dujardin</name><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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